Analysis ofLOXL1single nucleotide polymorphisms in Polish population with pseudoexfoliation syndrome
نویسندگان
چکیده
منابع مشابه
Association of non-synonymous single nucleotide polymorphisms in the LOXL1 gene with pseudoexfoliation syndrome in India
PURPOSE In the Icelandic and Swedish populations, pseudoexfoliation syndrome (XFS) and pseudoexfoliation glaucoma (XFG) has been significantly associated with LOXL1 exon 1 polymorphisms - allele G of rs1048661 (R141L) and allele G of rs3825942 (G135D). In this study, we looked at the association of rs1048661 and rs3825942 in a southern Indian population. METHODS Fifty-two cases with XFS (incl...
متن کاملLysyl oxidase-like 1 polymorphisms in a southwestern Greek cataract population with pseudoexfoliation syndrome
PURPOSE The aim of this study was to determine the possible association of rs1048661 and rs3825942 single nucleotide polymorphisms (SNPs) in the lysyl oxidase-like 1 (LOXL1) gene of cataract patients from southwestern Greece with pseudoexfoliation (PEX) syndrome. PATIENTS AND METHODS Ninety-three patients with PEX syndrome and 74 without PEX syndrome were recruited with the principal diagnosi...
متن کاملPseudoexfoliation Syndrome in Diabetic Patients
OBJECTIVE: Pseudoexfoliation syndrome (PEX) leads to some problems in the eye surgery specially cataract surgery. As the prevalence of eye problems is high in diabetic patients, we meant to assess the prevalence of PEX in diabetic patients. MATERIALS AND METHODS: In this cross-sectional study, 400 type 2 diabetic patients aged 50 or above who referred to Yazd Diabetes Research Center were sele...
متن کاملAnalysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma
PURPOSE To identify if recently described LOXL1 (lysyl oxidase-like 1) polymorphisms are associated with pseudoexfoliation glaucoma (XFG) in a United States (U.S.) Caucasian patient population. METHODS Individuals with XFG were identified using standard clinical examination techniques. TaqMan allelic discrimination assays were used to genotype 13 single nucleotide polymorphisms (SNPs) that ta...
متن کاملAnalysis of LOXL1 polymorphisms in a Saudi Arabian population with pseudoexfoliation glaucoma
PURPOSE To investigate whether single nucleotide polymorphisms (SNPs) in the lysyl oxidase-like 1 (LOXL1) gene are associated with pseudoexfoliation glaucoma (PEG) in the Saudi Arabian population. METHODS The coding regions of LOXL1 were fully sequenced in 93 clinically diagnosed PEG patients and 101 healthy controls. Both groups were Saudi Arabs. Previously reported and newly identified SNPs...
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ژورنال
عنوان ژورنال: Acta Ophthalmologica
سال: 2011
ISSN: 1755-375X
DOI: 10.1111/j.1755-3768.2010.02083.x